• What exactly is DHA SendaBio?

DHA SendaBio is a DHA (docosahexaenoic acid) food supplement supplied in soft capsules for easy consumption. DHA is a substance that is essential and vital for our health which we have to get externally because our body is unable to synthesise it. DHA SendaBio is prepared from Omega 3 of the highest quality and purity on the market, the safest and most effective with the highest bioavailability. It is prepared from omega-3 of the highest quality and purity on the market, the safest and most effective with the highest bioavailability, in addition to having been developed to incorporate the lowest rates of phytanic acid on the market, taking into account that this is the highest cytotoxin, pro-oxidant and apoptosis-inducer found in our diet.
Phytanic acid is recognised in public health as a potential risk factor in neurological and visual disorders and an inducer of prostate, lung and colon cancer among others and DHA SendaBio has been developed with the aim of integrating minimum levels of it.

  • What is omega-3? Is DHA an omega-3?

So-called omega-3s are essential long-chain polyunsaturated fatty acids formed by joining a carboxyl group and a carbon chain of variable length.

DHA (docosahexaenoic acid) is an essential polyunsaturated fatty acid of the omega-3 series, consisting of 22 carbon atoms and 6 double bonds.

  • What are the differences between Omega-3 and Omega-6?

From the point of view of their nutritional use, fatty acids are in turn classified by their so-called families or series of fatty acids. The three major families are omega-9 as oleic acid (C18:1, AO), omega-6 as linoleic acid (C18:2, to) and finally the omega-3 family, with three important representatives – linolenic acid (C18:2, ALN), eicosapentaenoic acid (C20:5, EPA) and docosahexaenoic acid (C22:6 DHA).

  • When is it best to take DHA SendaBio

DHA SendaBio can be taken at any time of the day, although it is recommended to take it with meals to avoid any possible fishy after-taste. You can also take several perles at the same time or at different times, as its effect is cumulative over weeks or months in the tissues where it is necessary, i.e. it has a highly conservative metabolism but it is not toxic and there is no danger of overdosing.

  • How Much DHA SendaBio is recommended if I am pregnant or breastfeeding?

Humans first obtain DHA through the placenta and breast milk, whose levels of DHA are much higher than those of cow’s milk. DHA needs are particularly high in the last 3 months of pregnancy and during the first year of life, being an essential nutrient for visual and neurological development and foetal growth. That is why it is recommended to take DHA during pregnancy and breast-feeding.

Different epidemiological studies demonstrate the health benefits of taking omega-3 polyunsaturated fatty acids during pregnancy, such as reducing the risk of developing hypertension associated to pregnancy and postpartum depression, as well as the relationship with the increase in the length of pregnancy to reduce the prevalence of prematurity and low birth weight.

For an adequate nutritional status during pregnancy, it is recommended to take 2-3 perles per week, either all at once or spread over the week

  • Why does DHA SendaBio not have EPA like other supplements on the market?

The majority of fish oils that can be found on the market contain DHA and EPA. Its precursor is linolenic acid (ALA), but its conversion to EPA and DHA is very slow and, for reasons that are still not very well known, usually very low or absent. In fact, our body accumulates DHA but not EPA. The accumulation of EPA in the tissues only occurs when this fatty acid is consumed as such, because biochemically speaking it is only an intermediary in the formation of DHA and also a contaminant of DHA, since, at a higher dose of EPA, the bioavailability of DHA decreases in the body.

Moreover, EPA can be obtained from DHA through a process called «retro-conversion», as a result of which high levels of DHA ensure good levels of EPA, but not the reverse.

It is interesting to note that DHA, and not EPA, is at very high levels in breast milk, to meet the needs of infants. EPA is not present in the brain, retina, semen, etc., and recently clinical studies have found that only DHA levels, but not EPA, have antiatherogenic and cardioprotective activity.

Taking all this into account, at SendaBio we have seen the need for a product without intermediaries that the body is not going to use, thus increasing the quality of the product and reducing its cost, as the consumer is buying a pure product, free of metabolic intermediates with no biological function.

The reason why current omega-3 products on the market contain EPA is not justified from any therapeutic or clinical point of view, but rather due to the technical impossibility of obtaining a quality product free of EPA or an economic product without the standard of quality required.

  • Why is it important to supplement my diet with DHA SendaBio?

DHA cannot be effectively synthesised «de novo» in the human body and must be taken in the diet or through direct supplements. DHA is extremely rare in the diet, being almost exclusively in low concentration in egg yolk and some fish. As a result, the risk of DHA deficiency is high. The average diet, including the Mediterranean, is between 100-150 mg/day. For this reason, DHA is the only nutrient deficiency in practically the entire world population, with consumption below (half) the recommended dose worldwide, except in countries and regions such as Japan, Scandinavia or Iceland or in isolated communities such as the Inuit community (500-700 mg/day).

Dietary DHA is 100% of animal origin, since there is no DHA in foods of plant origin. Therefore, needs for vegetarians are much higher, particularly for vegans or non-consumers of egg.
The omega-3 consumption recommendations of the WHO, FAO, European associations and the American Heart Association vary between 1000 and 2000 mg/day, but never less than 250 mg in reference to the independent risk indicator for death at lower doses. In other words, an intake of below 250 mg/day is considered to be a risk factor for health

  • Can I take DHA SendaBio if I have an allergy to fish?

Although DHA SendaBio comes from an ultra-purification process, the starting material for its preparation is tuna. In cases of allergy to tuna or fish, we recommend carrying out specific allergy tests

  • What is phytanic acid?

Phytanic acid is a saturated fatty acid, which is present in small amounts in certain foods such as dairy products and the animal fat of ruminants and fish. Ordinary food contributes about 50 -100 micrograms daily. In addition to its contribution to diet, there are important interactions with food habits, medicines and common diseases that help its accumulation.

PHYTANIC ACID is the largest known cytotoxin, pro-oxidant and inducer of dietary oxidative stress and lipid peroxidation. Certain studies indicate how visual, olfactory and auditory ailments and certain diseases such as Alzheimer’s, as well as muscle, cardiovascular and fertility disorders may be induced by this product.

Moreover, phytanic acid is a potent antagonist of docosahexaenoic acid, reducing or cancelling out the effect that DHA has on inhibiting apoptosis and neuroinflammation.

Phytanic acid is a significant risk factor of tumours for cancers with a higher prevalence (prostate, breast, and colon among others) because it increases tumour activity, as a result of which the use of DHA supplements free of phytanic acid is necessary in cancer therapy.

In addition, it has a teratogenic effect, being particularly negative for foetuses and young children, which is important to take into account when deciding to provide a DHA supplement to children.

  • How can I give my baby SendaBio DHA if it is bottle-fed?

During childhood and neurological development, DHA needs may be higher. The baby will get all the DHA it needs through breast-feeding, but, in the case of artificial feeding, this does not have to change. You can burst a perle of DHA SendaBio and empty its contents into the bottle. It is preferable to separate part of the bottle, add the contents of the perle and give it to the baby and then give it the rest of the bottle, so as not to miss out on the DHA if it does not finish all of the contents.

With regard to the dose, 1-2 perles of DHA SendaBio a week is sufficient. It is important to emphasise that continued use of DHA can be considered safe as it does not compromise the weight and mental development of the child according to the Bayley Scale.

Taking DHA is recommended for school-age children, noting improvements in visual recognition and understanding, an improvement in reading and handling skills, increased learning capacity and academic performance and it acts as an adjuvant in the treatment of TDHA, without there being any changes in behaviour and hyperactivity.

  • What are the differences between DHA SendaBio and other omega-3 products on the market?

There are several differences that make DHA SendaBio a product which is more complete than others that can be found on the market:

  1. It is in the form of triglycerides (TG), i.e. in the same chemical form in which we eat it in our diet
  2. It is the product of the highest quality and purity on the market, the safest and most effective with the highest bioavailability.

Chemically speaking, there are many ways of getting a DHA molecule into the human body, but, for this molecule to be assimilated, it needs to be joined to an ethyl-ester or a glycerol forming a triglyceride. The forms of ethyl ester (EE), which are very common on the market, have low absorption into and bioavailability (73%) for the human body. However, the form of triglyceride (TG) like DHA SendaBio has significantly higher bioavailability. DHA SendaBio has the ultimate form of higher absorption and metabolisation with incorporation into the phospholipids in target tissues and the formation of neuroprotective docosanoids.

In order to ensure safety in the entire population and particularly in pregnant women, infants and children, DHA SendaBio complies scrupulously with the standards of quality and safety:

  1. it does not contain partially hydrogenated oils or fats
  2. it is free of ethanol, unlike EE (ethyl-ester) compounds that exist on the market
  3. it is free of heavy metals (mercury, lead, cadmium, arsenic…) dioxins, furans and PCBs
  4. it is one of the DHA products with the least amount of phytanic acid on the market.